Leflunomide 20MG

A prescription medication used for treating diseases like autoimmune conditions. They are classified as disease-modifying antirheumatic drugs. They attack the disease by reducing inflammation and slowing the progression of joint damage caused by an overactive immune system. 

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Components of Leflunomide 20MG

Leflunomide (20 mg): A disease-modifying antirheumatic drug (DMARD) that is rapidly converted in the body to its active metabolite, teriflunomide (also known as A77 1726). It works by inhibiting the enzyme dihydroorotate dehydrogenase, which reduces the production of pyrimidine needed for the growth of inflammatory white blood cells. 

Lactose Monohydrate: Used as a filler or diluent; 20 mg tablets typically contain between 36 mg and 152 mg of lactose.

Maize Starch (including Pregelatinized Starch): Acts as a binder and disintegrant to help the tablet hold together and later break down.

Crospovidone: A "super-disintegrant" that helps the tablet dissolve quickly.

Magnesium Stearate: A lubricant that prevents the tablet from sticking to machinery during manufacturing.

Colloidal Anhydrous Silica: Enhances the flow of ingredients during the manufacturing process. 

Uses of Leflunomide 20MG

Rheumatoid Arthritis (RA): Used to reduce signs and symptoms, improve physical function, and retard structural damage in moderate to severe active RA.

Psoriatic Arthritis (PsA): Helps manage joint inflammation and associated skin lesions for those with psoriatic arthritis.

Off-label Uses: Sometimes prescribed for other autoimmune conditions such as Crohn's disease or lupus, though these uses require careful specialist supervision. 

Partner with Bendic Healthcare for Leflunomide 20MG

Bendic Health Care Pvt. Ltd. is making its way to the top of the Indian Best Pharmaceutical companies by offering the pharma range at a very affordable price. Here at Bendic, we have the best manufacturing facility in the state with the best professional team. Also, we are not only competitive with the domestic companies but also internationally. Bendic Health Care has a Quality Assurance and Quality Control facility in our manufacturing unit. Moreover, we followed industrial norms and regulations at the global level for the premium. 

• The company has a manufacturing plant with a state-of-the-art infrastructure.
• Wide range of pharma products. 
• All medicines are 100% safe and effective
• ISO-WHO-GMP-certified pharmaceutical company 
• Affordable Range
• Has a Quality Assurance & Quality Control facility
• Patient-Centric approach

Some Common Side Effects of Leflunomide 20MG

Diarrhea: The most common side effect, affecting up to 27% of patients. It often improves over time or can be managed with over-the-counter medications like loperamide.

Nausea and Vomiting: Gastrointestinal upset is common and may be reduced by taking the medication with food.

Headache and Dizziness: These symptoms are often temporary and may resolve as treatment continues.

Skin Rash: Mild rashes are common, occurring in up to 12% of patients.

Hair Loss or Thinning: Reversible thinning of the hair is reported by some patients.

High Blood Pressure: Leflunomide can cause a slight increase in blood pressure, necessitating regular monitoring.

Abnormal Liver Enzyme Levels: Elevated liver enzymes are common and are usually monitored through regular blood tests.

Weight Loss: Some patients may experience minor, unexplained weight loss, often due to a loss of appetite

Frequently Asked Questions

What are Leflunomide Tablets IP used for?

Leflunomide Tablets IP are primarily used to treat autoimmune conditions such as rheumatoid arthritis and psoriatic arthritis. The medicine helps reduce joint inflammation, swelling, pain, and stiffness while slowing the progression of joint damage.

How do Leflunomide Tablets work?

Leflunomide works by suppressing the overactive immune system responsible for inflammation in autoimmune diseases. It blocks certain enzymes required for immune cell growth, thereby reducing inflammation and preventing joint damage.

How should Leflunomide Tablets be taken?

Leflunomide tablets are usually taken once daily or as prescribed by a doctor. The tablet should be swallowed whole with water and can be taken with or without food. Always follow your doctor’s dosage instructions.

How long does Leflunomide take to start working?

Leflunomide may start showing improvement in symptoms within 4–6 weeks, but the full therapeutic effect may take several months. Patients are advised to continue the medication as prescribed for the best results.

What are the common side effects of Leflunomide Tablets?

Common side effects may include nausea, diarrhea, headache, stomach discomfort, rash, and hair thinning. Most side effects are mild and improve over time, but medical advice should be sought if they persist.

Can Leflunomide be taken during pregnancy?

No. Leflunomide is not recommended during pregnancy because it may cause serious harm to the unborn baby. Women planning a pregnancy should consult a doctor before taking this medication.

Is Leflunomide safe for long-term use?

Yes, Leflunomide is often prescribed as a long-term treatment for autoimmune arthritis. However, regular monitoring, such as liver function tests and blood tests, may be required during treatment.